| Name in Polish : | Toksykologia |
| Name in English : | Toxicology |
| Main field of study (if applicable): | Environmental Engineering |
| Specialization (if applicable) : | Environmental Quality Management |
| Level : | II |
| Form: | full-time |
| Kind of subject : | obligatory |
| Subject code : | ISS105031 |
|
Lecture |
Classes |
Laboratory |
Project |
Seminar |
|---|---|---|---|---|---|
Number of hours of organized classes in University (ZZU) |
15 | 15 | |||
Number of hours of total student workload (CNPS) |
30 | 30 | |||
Form of crediting |
Crediting with grade | Crediting with grade | |||
| Group of courses | |||||
Number of ECTS points |
1 | 1 | |||
including number of ECTS points for practical(P) classes |
1 | ||||
including number of ECTS points for direct teacher–student contact (BK) classes |
0.5 | NAN | 0.5 | NAN | NAN |
| PREREQUISITES RELATING TO KNOWLEDGE, SKILLS AND OTHER COMPETENCES | |
|---|---|
| 1 | To have a basic knowledge in biology, microbiology, biochemistry |
| SUBJECT OBJECTIVES | |
|---|---|
| C1 | Acquisition of knowledge concerning the origin and poisons types. |
| C2 | Entering ways of poisons into the human body and their transformations inside the body. |
| C3 | Acquisition of knowledge concerning the influence of physical, chemical and biological factors on the substance toxicity. |
| C4 | Acquisition of knowledge concerning the influence of physical, chemical and biological factors on the substance toxicity. |
| C5 | Acquisition of knowledge about the presence of poisons in the environment and their influence on aquatic ecosystems, soil and air quality |
| C6 | Knowledge of influence of ionising radiations to life forms |
| C7 | Purchasing the ability of examining the toxic properties of substances. |
| C8 | Purchasing the ability of examining the mutagenic properties of substances |
| C9 | Purchasing the ability of examining of the impact of physical and chemical factors on poisons toxicity. |
| C10 | Purchasing the ability of performing toxicological analysis of environmental samples |
SUBJECT EDUCATIONAL EFFECTS | |
|---|---|
| relating to knowledge: | |
| PEK W01 | has a basic knowledge about the origin and poisons types |
| PEK W02 | knows the ways of entering poisons into the human body |
| PEK W03 | knows mechanisms of the biotransformation and expelling poisons |
| PEK W04 | has a basic knowledge about the influence of biological and physicochemical factors on substance toxicity |
| PEK W05 | knows the mechanism of toxic, mutagenic, carcinogenic and teratogenic acting of poisons |
| PEK W06 | knows methods of toxicity assessment of substances and toxicological interactions |
| PEK W07 | knows the influence of poisons on aquatic and soil ecosystems |
| PEK W08 | has a basic knowledge about the biological monitoring |
| PEK W09 | knows effects of the influence of ionising radiations to life forms. |
| relating to skills: | |
| PEK U01 | is able to select and to multiply the biological material for tox screens |
| PEK U02 | is able to carry out tests in order to determine the acute toxicity of substances |
| PEK U03 | is able to carry out tests in order to determine the sublethal and chronic toxicity of substances |
| PEK U04 | is able to perform ecotoxicological examinations of water, soil, air and waste |
| PEK U05 | is able to detect the presence of mutagenic substances in environmental samples. |
| relating to social competences: | |
| PEK K01 | is conscious of threats to people and natural environment of chemical pollutions associated with emission. |
PROGRAMME CONTENT |
||
Form of classes - lecture |
Number of hours |
|
| Wy1 | Sources and types of poisons. | 1 |
| Wy2 | Definition of poison. Dose. Biological factors and physicochemical determining the toxicity. | 1 |
| Wy3 | Absorption, ramoval and transport and distribution of xenobiotics in the body. | 1 |
| Wy4 | Biotransformation of xenobiotics | 1 |
| Wy5 | Removal of poisons | 1 |
| Wy6 | Mechanisms of toxic effect of poisons. | 1 |
| Wy7 | Mutagenic, carcinogenic and teratogenic action of substances | 1 |
| Wy8 | Methods of estimation of biological properties of substances. | 1 |
| Wy9 | Toxicological interactions. | 1 |
| Wy10 | The chemical contamination of air and its influence on life forms. | 1 |
| Wy11 | Toxic pollutants and their influence on aquatic ecosystem. | 1 |
| Wy12 | Causes of soil ecosystem degradations. | 1 |
| Wy13 | Toxicology of food. | 1 |
| Wy14 | Toxicology of ionising radiation. | 1 |
| Wy15 | Biological monitoring and its use for the evaluation of environment quality. Total credit. | 1 | Suma godzin | 15 |
PROGRAMME CONTENT |
||
Form of classes - laboratory |
Number of hours |
|
| La1 | The introduction, the scope of exercises and principles of BHP in the toxicological laboratory. Preparing the biological material for tox screens | 2 |
| La2 | Assessment of the impact of biological, physicochemical factors to the toxicity of xenobiotics. | 2 |
| La3 | Determination of toxic influence of chemical contaminations of the environment on life forms with the use of lethal tests. | 2 |
| La4 | Determination of toxic influence of chemical contaminations of the environment on life forms with the use of physiological tests | 2 |
| La5 | The use of indicator organisms for examination of soil and waste qual-ity | 2 |
| La6 | The use of indicator organisms for assessing the level of air contamination. | 2 |
| La7 | Methods of estimation of mutagenic and carcinogenic action of environmental contaminations | 2 |
| La8 | Crediting with grade. | 1 |
| Suma godzin | 15 | |
| TEACHING TOOLS USED | |
|---|---|
| N1 | Informative lecture |
| N2 | Presentation of conducting lethal tests |
| N3 | Presentation of conducting physiological tests |
| N4 | Presentation of conducting tests in order to determine the mutagenic properties of chemical com-pounds |
| N5 | Evaluation of environmental standards based on applicable standards |
| N6 | Preparation of report containing the summary of all examinations. |
| Evaluation (F - forming during semester), P - concluding (at semester end) | Educational effect number | Way of evaluating educational effect achievement | |
|---|---|---|---|
| 1 | P1 | PEK_W01, PEK_W02, PEK_W03, PEK_W04, PEK_W05, PEK_W06, PEK_W07, PEK_W08, PEK_W09, PEK_K01 | Test |
| 2 | F1 | PEK_U01 | Credit |
| 3 | F2 | PEK_U02 | Credit |
| 4 | F3 | PEK_U03 | Credit |
| 5 | F4 | PEK_U04 | Credit |
| 6 | F5 | PEK_U05 | Credit |
| P2 = 0,125F1 + 0,125F2 + 0,125F3 + 0,125F4 +0,125F5 | |||
| Primary literature: | |
|---|---|
| Primary literature: | Hodgson E., A textbook of modern toxicology, Wiley interscience, Hoboken, New Jersey, 2004. |
| Primary literature: | Rybak J., Kołwzan B., Ecotoxicology : course in English : theory and laboratory practice. Łódź : PRINTPAP, 2011 |
| Secondary literature: | |
| Secondary literature: | Wright DA, Welbourn P, Environmental Toxicology (Cambridge Environmental Chemistry, Cambridge university Press, 2002. |
| Name and surname: | Justyna Rybak, Grzegorz Pasternak |
| E-mail: | justyna.rybak@pwr.wroc.pl ;grzegorz.pasternak@pwr.wroc.pl |
| Nr | Subject educational effect | Correlation between subject educational effect and educational effects defined for main field of study and specialization (if applicable)** | Subject objectives*** | Programme content*** | Teaching tool number*** |
|---|---|---|---|---|---|
| 1 | PEK_W01 | K2IS_W09, S2EQM_W05 | C1 | Lec1 | N1 |
| 2 | PEK_W02 | K2IS_W09, S2EQM_W05 | C2 | Lec3 | N1 |
| 3 | PEK_W03 | K2IS_W09, S2EQM_W05 | C2 | Lec4,5 | N1 |
| 4 | PEK_W04 | K2IS_W09, S2EQM_W05 | C3 | Lec2 | N1 |
| 5 | PEK_W05 | K2IS_W09, S2EQM_W05 | C4 | Lec6-7 | N1 |
| 6 | PEK_W06 | K2IS_W09 K2IS_W01, S2EQM_W05 | C4 | Lec8-9 | N1 |
| 7 | PEK_W07 | K2IS_W09, S2EQM_W05 | C5 | Lec10,11,12 | N1 |
| 8 | PEK_W08 | K2IS_W09, S2EQM_W05 | C5 | Lec15 | N1 |
| 9 | PEK_W09 | K2IS_W09, S2EQM_W05 | C6 | Lec14 | N1 |
| 10 | PEK_U01 | K2IS_U01, K2IS_U04, S2EQM_U02 | C7-8 | Lab1 | N2,N3 |
| 11 | PEK_U02 | K2IS_U01, K2IS_U04, S2EQM_U02 | C6 | Lab3 | N2 |
| 12 | PEK_U03 | K2IS_U01, K2IS_U04, S2EQM_U02 | C7 | Lab4 | N3 |
| 13 | PEK_U04 | K2IS_U01, K2IS_U04, S2EQM_U02 | C7 | Lab3,4,5,6 | N2,N3, N5 |
| 14 | PEK_U05 | K2IS_U01, K2IS_U04, S2EQM_U02 | C8 | Lab7 | N4,N6 |
| 15 | PEK_K01 | K2IS_K02 | C3 | Lec7,Lec10,Lec11,Lec12 | N1 |